Due to a multitude of factors, the elderly are more likely to develop cognitive impairment and dementia. As of now, there are no effective ways to prevent cognitive deterioration.
If doctors are unable to give pharmaceutical therapy, patients and their families may turn to complementary and alternative medicine for cognitive preservation.
Dietary supplements are the most common complementary and alternative medicine people take, despite the fact that data for their probable interactions with other therapy is still lacking.
Despite the lack of scientific evidence, doctors should be aware of the potential benefits and hazards of dietary supplements and counsel their patients on how to take them safely (1)
Because cognitive decline is so common and has such devastating consequences, it’s understandable that older people believe it’s important to be intellectually fit as they age. 
Due to the paucity of research on the subject, many elderly people are turning to complementary and alternative medicine (CAM) in an attempt to maintain their cognitive function.
Nearly four out of ten Americans have used complementary and alternative medicine (CAM) in the last year, according to a new national poll. 
In a community of older residents, 52% of those using prescription medications also used nutritional supplements. There are a wide variety of dietary supplements on the market, which include vitamins and minerals, herbs and botanicals, as well as amino acids.  
To avoid potentially harmful interactions between complementary and alternative medicine (CAM) and other treatments, physicians must be aware that their patients may be using CAM. Consequently, our purpose is to review the most recent studies on cognitive health supplements to discover if there is any evidence of benefit or harm.
Every nutritional supplement’s common and chemical names, as well as terms like “cognition,” “cognitive impairment,” and “memory loss,” were searched for.
According to the strength of the evidence, articles were selected for inclusion.
Systematic reviews of randomised controlled trials and reports of randomised controlled trials were frequently highlighted in compared to observational studies.
Supplements for memory and cognition can help certain people, but only to a limited extent:
These include fish oil, B vitamins, cocoa flavanols, curcumin (a molecule found in the spice turmeric), huperziine A, vinpocetine, and acetyl-L-carnitine, to mention just a few.
Certain scenarios may necessitate the employment of both: Studies suggest that fish oil may be therapeutic for Alzheimer’s patients who have adequate levels of B vitamins.
Taking magnesium supplements may help older people with a high calcium to magnesium intake ratio improve their cognitive abilities, according to studies.
Memory loss associated with statins may be reduced by CoQ10 supplementation.
Some forms of choline have been demonstrated to improve short-term memory and focus in elderly people with mild to severe Alzheimer’s disease.
Other kinds of choline have not had the same effect on those who have taken them. Women who are anaemic (deficient in iron) may benefit from taking iron supplements.
Probiotic supplements may improve general cognition when taken by older adults with cognitive impairment, but not healthy seniors.
It has been claimed that drinking green tea can increase cognitive performance, although this has not been confirmed. Gingko biloba and vitamin E haven’t been demonstrated to be effective brain-enhancing drugs.
Researchers have focused mostly on healthy adults with no memory or cognitive issues while studying the herb Bacop (Boerhaavia monnieri). There have been no conclusive outcomes from the study.
It is possible that some proprietary formulas, such as Procera AVH, give more advantages than the clinical evidence suggests.
Consider these assertions with caution. The Food and Drug Administration has issued a warning against “false hope” supplements that claim to treat Alzheimer’s and dementia. It is recommended that persons with brain injuries not use any substances that claim to assist prevent or treat them.
Vinpocetine, a substance included in memory supplements like Procera AVH and Alpha Brain, has been related to foetal harm and miscarriage. This supplement is not recommended for pregnant or lactating women.
So, it may interact with other blood-thinning supplements and pharmaceuticals, such as aspirin, clopidogree, ticlopidine (Ticlid), and pentoxifylline (Trental), all of which can inhibit platelet aggregation and produce blood clots, resulting in a potentially dangerous combination.
Be aware that certain supplements that claim to aid memory and cognition contain drugs that have not been authorised by the FDA and cannot be sold as dietary supplement ingredients. Avoid them at all costs! Noopept (omberacetam) and its equivalents, such as oxiracetam, aniracetam, and phenylpiracetam, are examples of these medicines (a piracetam analogue).
If you’d like more information on the potential benefits of these supplements, click on the links above.
Discover which minerals experts recommend avoiding for those at risk of Alzheimer’s disease by reading up on the benefits of magnolia bark extract, ketone supplements, foods (like blueberries, strawberries, and red wine), and diets, such as the Mediterranean diet and the MIND diet (Mediterranean-DASH Diet Intervention for Neurodegenerative Delay). Please log in to find out more.
A lack of magnesium can have a negative impact on the health of brain cells.
It has been shown in several research that magnesium supplements can enhance cognitive function and reduce the risk of developing dementia.
On the other hand, too much magnesium has never been shown to be better at crossing the blood-brain barrier to reach the brain — even though some varieties of magnesium are better absorbed from the stomach than other types.
In many enzymatic activities, magnesium is a divalent cation. Magnesium sulphate, magnesium citrate, magnesium biglycinate, and magnesium-Lthreonate are all forms of magnesium accessible.
People with dementia have been proven to benefit from taking magnesium supplements, according to human research.
It has not been established that magnesium supplementation helps people with dementia.
A recent review of 13 studies found no difference in magnesium levels between Alzheimer’s patients and healthy people.
The brain fluid and hair of Alzheimer’s disease sufferers contain a reduced concentration of magnesium compared to those of healthy individuals (Veronese et al, 2016).
Human studies have shown that taking magnesium supplements may help prevent dementia.
Magnesium L-threonate (MgT) was supplied to 44 people with memory concerns, anxiety, and sleep issues in a 12-week pilot RCT.
According to the study’s findings, MgT patients showed an overall improvement in cognitive performance compared to controls (Liu et al, 2015).
Magnesium has not been explored in human therapeutic trials to see if it prevents dementia or cognitive impairment by boosting magnesium levels numerically.
Magnesium is a vitally important nutrient. But excess magnesium in the blood can be harmful.
Hypermagnesemia is the medical word for this condition, which can be brought on by a magnesium deficiency.
High doses of magnesium may cause kidney damage, especially in the elderly or those with pre-existing renal problems. Safety: Safe when used to treat or prevent magnesium shortage.
A dietary excess of magnesium poses virtually little risk.
If the body has absorbed an excessive amount of magnesium, a person may experience any or all of the following symptoms:
Facial flushing due to exhaustion diarrhoea pains in the stomach nausea vomiting depressive thoughts muscular tremors
blood pressure is low urinary incontinence and difficulty breathing a heart attack.
Magnesium overdoses in otherwise healthy individuals are quite unusual. If you consume too much magnesium through your food, it isn’t usually a problem.
Magnesium supplements and medications can cause mild overdose symptoms, such as diarrhoea, nausea, and stomach cramps, when taken in high doses.
If you’re experiencing any of these signs and symptoms, magnesium in the following forms is most likely to be to blame:
Salt of magnesia, chloride of magnesium, The magnesium gluconate and magnesium oxide
Supplements and medications that contain more than 5,000 mg of magnesium per day are quite rare. Magnesium poisoning might result from this. Laxatives and antacids are the most common medications used.
Magnesium is excreted via the kidneys, thus patients with kidney disease or failure are more prone to have excessive magnesium absorption.
Magnesium supplements and medicines are generally discouraged for those with this risk.